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4 days ago

Feline lymphoma???Signalment: 7 year old MN indoor DSH. Currently dealing with military dermatitis and fleas (not on prevention). P has been losing wt for the last month (1.5/ 5 BCS). E/D okay, no V/D. Mild lethargy. P has enlarged prominent inguinal LNs (2.5cm × 1.3cm x 1cm) and submandibular feel slightly firmer than normal. Abdominal palpation does feel to have enlarged LNs present. Remainder of PE was unremarkable. Bloodwork showed anemia, and leukocytosis (neutrophilia, mild monocytosis, prominent basophilia). Chem was unremarkable. Triple snap showed FIV positive. Fecal was neg.I am suspicious of feline lymphoma. Took FNA of inguinal LNs. It looks suspicious to me with a few mitosis figures noted, but I am unsure if it is more neoplastic or reactive? ... See MoreSee Less
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Coronation of Queen Elisabeth II 👸🏼(multinucleated crown cell in a cytology sample from a perivascular wall tumour in a dog) #veterinarycytology Photo courtesy of Cesare De Tommaso ... See MoreSee Less
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2 weeks ago

Colour blindness. One of my colleagues working on building inclusive visual exam questions has asked me a question and I thought some-one in here might know more about than I do. The question is whether people who are "colour blind" are limited in their ability to interpret Romanowsky or Gram (or other microscope stains). I have assumed that although colour perception will be different, there would still be enough difference in what is seen to still be able to do interpretative work but I realised that I have no real basis for my assumptions. Can anyone share their experience of colour blindness in cytology or know of people that manage (or that can't manage)? ... See MoreSee Less
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If learning cytology and haematology is one of your goals for 2021, you may be happy to know we have a wide selection of online courses for you. You will have webinars to watch, course notes to read and lots of digital cytology/haematology cases to solve that will give you the same experience as being in front of the microscope 🔬. You will be tutored by a specialist in Clinical Pathology that will answer all your questions and will help you in the process of understanding these subjects and writing reports. I am looking forward to meeting you online 🧑‍💻...and hopefully one day to meet you in person too 💁‍♂️ FrancescoFor more information and registrations, follow this link: vetcpd.co.uk/online-courses-on-demand/ ... See MoreSee Less
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THE MATCHING PAIR Signalment: Dog, Rottweiler, female, 5-year-old. Clinical history rapid onset of lethargy and inappetence. Explorable lymph nodes not enlargedHaematology and biochemistry: clinical biochemistry unremarkable. Haematology: mild normocytic normochromic anaemia (HCT 31.4%), marked leukocytosis (173.1 x 10^9/L) and mild thrombocytopenia (158 x 10^9/L, no clumps). Morphological evaluation of the blood smear revealed a predominant population of atypical haematopoietic cells (159 x 10^9/L), presumably lymphoid, intermediate to large in size, characterized by pleomorphic large nuclei, with coarse granular chromatin, and sometimes visible nucleoli. Cytoplasm is scant and basophilic with defined borders. Compatible with lymphoproliferative disorder, likely lymphoid leukaemia Vs leukaemic lymphoma. Recommended clinical staging, immunophenotyping (by cytofluorimetry) and cytological examination of bone marrow.Diagnostic imaging: chest x-rays and abdominal ultrasound both unremarkable.Immunophenotype by flow cytometry not availableBone marrow examination (cytology): hyper cellular sample of excellent quality. Prevalent population (80-90 %) of immature, medium to large, atypical lymphoid like elements. Sporadic precursors of erythroid, myelo-monocytic and megakaryocytic origin. Variable numbers of small lymphocytes and mature plasma cells also noted.Clinical picture and cell morphology were considered highly suggestive of acute lymphoblastic leukemia (ALL).Courtesy of Paola Ghergo (ACV Triggiano) ... See MoreSee Less
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